inDrop™ System
The inDrop ™ System is the only scRNA-Seq platform that provides enhanced experimental control, more actionable information and a lower overall cost per result compared to other existing platforms.
Scientists can now conduct more studies looking at more cells to gain more insights.

inDrop Highlights
Less expensive to run more samples
Flexibility with design experiments
Ability to process challenging samples
Maximize data from clinical samples
System Advantages
- The Industry's Highest Encapsulation Rates: >90% with low doublet
- More Actionable Info: Rare cell subpopulations and low abundant, bias-free transcripts
- Versatile Input Requirements: Diverse cell types, sizes and quantities
- Low Overall Cost Per Result: As low as 5¢ per cell
Diverse Applications
- Cancer: Tumor profiling
- Immunobiology: B-cell and T-cell receptor analysis
- Drug Discovery: Identification and validation of new drug targets
- Stem Cell: Cell-to-cell variation identification
- Developmental Biology: Cell lineage tracing

inDrop Workflow
Step 1

Step 2

Step 3

Step 2

Science
Publications
A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. [Epub ahead of print] PMID: 27667365
Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I.;
Cell Syst. 2016 Sep 21. pii: S2405-4712(16)30266-6. doi:
10.1016/j.cels.2016.08.011.
Droplet Barcoding For Single-Cell Transcriptomics Applied To Embryonic Stem Cells
Klein et al.
2015, Cell 161, 1187-1201
Marrying Microfluidics and Barcoding Technology
Cell, May 21, 2015, 161, Issue 5
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.
Derr et al.
2016, Genome Research 26(10): 1397-1410. Epub 2016 Jul 28
Protocols
Download the 1Cell scRNA-seq Pipeline Manual (version 1.0) [PDF, 209kB]
Download the inDrop™ Single-Cell Reverse Transcription Protocol (version 2.1) [PDF, 586kB]
Download the Training inDrop™ Reverse Transcription Protocol (version 2.1) [PDF, 568kB]
Download the inDrop™ Library Preparation Protocol (version 1.2) [PDF, 517kB]
Download the Sequencing Guidelines for Libraries (version 2.0) [PDF, 169kB]
Download the Primer Sequences for inDrop™ (version 2.0) [PDF, 206kB]
Download the Silanization Protocol (version 4.0) [PDF, 311kB]
Bioinformatics
Download the ESAT code [GitHub]
See the Publications section for the original paper.